DDB1單克隆抗體（CUSABIO貨號(hào)：CSB-MA107146）是一款特異性識(shí)別DDB1蛋白的高品質(zhì)科研試劑，適用于人類、小鼠、猴及大鼠等多物種樣本的ELISA和Western Blot檢測(cè)。DDB1作為DNA損傷結(jié)合蛋白的核心組分，通過與CUL4A等分子形成復(fù)合體，在紫外線誘導(dǎo)的DNA損傷修復(fù)、細(xì)胞周期調(diào)控及基因組穩(wěn)定性維持中發(fā)揮關(guān)鍵作用。本產(chǎn)品采用單克隆抗體技術(shù)制備，具有高親和力與優(yōu)異批間穩(wěn)定性，能精準(zhǔn)識(shí)別目標(biāo)蛋白的特定抗原表位，為研究DNA修復(fù)機(jī)制、腫瘤發(fā)生發(fā)展及細(xì)胞周期相關(guān)疾病提供可靠工具。在應(yīng)用場(chǎng)景上，該抗體適用于檢測(cè)細(xì)胞裂解液或組織樣本中內(nèi)源性DDB1蛋白的表達(dá)水平，廣泛用于分子生物學(xué)實(shí)驗(yàn)、癌癥信號(hào)通路研究以及遺傳毒性藥物開發(fā)等科研領(lǐng)域。通過優(yōu)化實(shí)驗(yàn)條件，研究者可借助該抗體高效完成蛋白質(zhì)相互作用分析、功能驗(yàn)證實(shí)驗(yàn)及分子機(jī)制探索，為揭示DDB1在DNA損傷響應(yīng)中的分子網(wǎng)絡(luò)提供技術(shù)支持。

Damage specific DNA binding protein 1; Damage-specific DNA-binding protein 1; DDB 1; DDB p127 subunit; Ddb1; DDB1_HUMAN; DDBa; DNA damage binding protein 1; DNA damage-binding protein 1; DNA damage-binding protein a; HBV X-associated protein 1;

Mouse

Human,Mouse,Monkey,Rat

Purified recombinant Human DDB1 protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG2b

12E1

It differs from different batches. Please contact us to confirm it.

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

ELISA,WB

Application	Recommended Dilution
WB	1:500-1:5000

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.