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  4. CWC27 Monoclonal Antibody

CWC27 Monoclonal Antibody

  • 中文名稱(chēng)：
    CWC27 Monoclonal Antibody
  • 貨號(hào)：
    CSB-MA574768
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of CD2 expression in Jurkat cells using CD2 antibody. Green, isotype control; red, CD2.
    • Immunocytochemical staining of HepG2 cells with CWC27 antibody. Nuclei were stained blue with DAPI; CWC27 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain:. Scale bar, 20 μm.
    • Western blotting analysis using CWC27 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with CWC27 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Mouse anti-Homo sapiens (Human) CWC27 Monoclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    CWC27; CWC27 Spliceosome Associated Cyclophilin; Serologically Defined Colon Cancer Antigen 10; SDCCAG-10; NY-CO-10; SDCCAG10; Probable Inactive Peptidyl-Prolyl Cis-Trans Isomerase CWC27 Homolog; CWC27 Spliceosome Associated Protein Homolog; Spliceosome-Associated Protein CWC27 Homolog; Antigen NY-CO-10; PPIase CWC27; CWC27 Spliceosome-Associated Protein Homolog (S. Cerevisiae); Peptidyl-Prolyl Cis-Trans Isomerase CWC27 Homolog; CWC27 Spliceosome-Associated Protein Homolog; Peptidyl-Prolyl Cis-Trans Isomerase SDCCAG10; PPIase SDCCAG10; RPSKA
  • 宿主：
    Mouse
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human CWC27 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類(lèi)型：
    Monoclonal
  • 抗體亞型：
    Mouse IgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    9F6
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2500
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
  • 基因功能參考文獻(xiàn)：
    1. CWC27 overexpression is associated with Bladder Cancer. PMID: 27206850
    2. By whole-exome sequencing, recessive protein-truncating mutations in CWC27 were found in seven unrelated families that show a range of clinical phenotypes, including retinal degeneration, brachydactyly, craniofacial abnormalities, short stature, and neurologic defects. PMID: 28285769
    3. The crystal structure of a relatively protease-resistant N-terminal fragment of human Cwc27 containing the cyclophilin-type peptidyl-prolyl cis-trans isomerase domain was determined at 2.0 A resolution. PMID: 25478830
  • 相關(guān)疾?。?/div>
    Retinitis pigmentosa with or without skeletal anomalies (RPSKA)
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Cyclophilin-type PPIase family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 10664

    OMIM: 250410

    KEGG: hsa:10283

    STRING: 9606.ENSP00000370460

    UniGene: Hs.371372



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