Recombinant Rhesus Macaque Interleukin-4 protein (IL4)

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產(chǎn)品詳情

純度：

>96% as determined by SDS-PAGE.
內(nèi)毒素：

Less than 1.0 EU/μg as determined by LAL method.
生物活性：

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1.0 ng/ml, corresponding to a specific activity of >1.0x10⁶ IU/mg.
基因名：

IL4
Uniprot No.：

P51492
別名：

IL4Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1
種屬：

Macaca mulatta (Rhesus macaque)
蛋白長度：

Full Length of Mature Protein
來源：

E.Coli
分子量：

14.9 kDa
表達區(qū)域：

25-153aa
氨基酸序列

HNCHIALREI IETLNSLTEQ KTLCTKLTIT DILAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE DFLERLKTIM REKYSKCSS
蛋白標簽：

Tag-Free
產(chǎn)品提供形式：

Liquid or Lyophilized powder
緩沖液：

0.2 μm filtered 2 x PBS, pH 7.4, 5 % trehalose ,lyophilized
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

5-10 business days
Datasheet & COA：

Please contact us to get it.

功能：

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
亞細胞定位：

Secreted.
蛋白家族：

IL-4/IL-13 family
數(shù)據(jù)庫鏈接：

STRING: 9544.ENSMMUP00000004187

UniGene: Mmu.3375