Mouse sex hormone-binding globulin,SHBG ELISA Kit
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中文名稱:小鼠性激素結(jié)合球蛋白(SHBG)酶聯(lián)免疫試劑盒
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貨號:CSB-E08233m
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樣本類型:serum, plasma
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檢測范圍:1 ng/mL-50 ng/mL
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靈敏度:0.5 ng/mL
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規(guī)格:96T/48T
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價格:¥3800/¥2500
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促銷:
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:小鼠性激素結(jié)合球蛋白(SHBG)酶聯(lián)免疫試劑盒(CSB-E08233m)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿樣本中的SHBG含量。SHBG即性激素結(jié)合球蛋白,它能特異性結(jié)合雄激素和雌激素,調(diào)控性激素在體內(nèi)的活性。近年來研究發(fā)現(xiàn)其與多種疾病相關(guān),如多囊卵巢綜合征、代謝綜合征等。深入研究其作用機制,或可助力相關(guān)疾病的早期診斷、病情評估及治療靶點開發(fā)。試劑盒檢測范圍為1.3 ng/mL-50 ng/mL,適用于研究性激素代謝調(diào)控機制、生殖系統(tǒng)疾病模型構(gòu)建、內(nèi)分泌干擾物評估等基礎科研場景,可滿足實驗室對小鼠生殖內(nèi)分泌相關(guān)研究的定量檢測需求,為探索激素依賴性生理病理過程提供可靠工具。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名:Shbg ELISA Kit; Sex hormone-binding globulin ELISA Kit; SHBG ELISA Kit; Sex steroid-binding protein ELISA Kit; SBP ELISA Kit; Testis-specific androgen-binding protein ELISA Kit; ABP ELISA Kit
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縮寫:SHBG
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Uniprot No.:
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種屬:Mus musculus (Mouse)
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反應時間:1-5h
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上樣量:50-100ul
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檢測波長:450 nm
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研究領(lǐng)域:Signal Transduction
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測定原理:quantitative
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測定方法:Sandwich
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精密度:
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線性度:
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回收率:
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標準曲線:
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數(shù)據(jù)處理:
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貨期:3-5 working days
相關(guān)產(chǎn)品
靶點詳情
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功能:Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
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基因功能參考文獻:
- SHBG suppresses inflammation and lipid accumulation in macrophages and adipocytes, which might be among the mechanisms underlying the protective effect of SHBG, that is, its actions which reduce the incidence of metabolic syndrome PMID: 30046278
- A wave of apoptosis during the pre-pubertal period is required for normal spermatogenesis to develop, and our data indicate that this apoptotic wave may be regulated by ABP and/or androgens. PMID: 12831397
- USF transcription factors repress SHBG transcription in Sertoli cells through an interaction with FP4 within its proximal promoter PMID: 15574421
- monosaccharide-induced lipogenesis reduced hepatic HNF-4alpha levels, which in turn attenuated SHBG expression. PMID: 17992261
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亞細胞定位:Secreted.
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數(shù)據(jù)庫鏈接:
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