Mouse Apolipoprotein A-I-binding protein(APOA1BP) ELISA kit

文獻引用 (1) 說明書下載

產(chǎn)品詳情

產(chǎn)品描述：

小鼠載脂蛋白A-I結(jié)合蛋白(APOA1BP)酶聯(lián)免疫試劑盒（CSB-EL001914MO）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的APOA1BP含量。試劑盒檢測范圍為9.38 pg/ml-600 pg/ml，適用于脂代謝機制研究、動脈粥樣硬化模型評估、肝臟功能分析等基礎(chǔ)科研領(lǐng)域。為探索脂質(zhì)代謝相關(guān)信號通路及疾病模型研究提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
別名：

Naxe ELISA Kit; Aibp ELISA Kit; Apoa1bp ELISA Kit; NAD(P)H-hydrate epimerase ELISA Kit; EC 5.1.99.6 ELISA Kit; Apolipoprotein A-I-binding protein ELISA Kit; AI-BP ELISA Kit; NAD(P)HX epimerase ELISA Kit
縮寫：

APOA1BP
Uniprot No.：

Q8K4Z3
種屬：

Mus musculus (Mouse)
反應(yīng)時間：

1-5h
上樣量：

50-100ul
檢測波長：

450 nm
研究領(lǐng)域：

Cardiovascular
測定原理：

quantitative
測定方法：

Sandwich
精密度：
線性度：
回收率：
數(shù)據(jù)處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

功能：

Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
基因功能參考文獻：
1. Loss of Apoa1bp increased vascular density and facilitated the recovery of blood vessel perfusion function in a hindlimb ischemia model. PMID: 28325782
2. The Aibp gene encodes two different proteins, both targeted to the mitochondria (mAIBP) and cytosol (cAIBP) confirming the presence of dehydratase and epimerase in the cytosol and mitochondria. PMID: 24611804
3. AI-BP plays an important role in capacitation possibly providing a link between protein phosphorylation and cholesterol efflux. PMID: 18202122
亞細胞定位：

Mitochondrion. Secreted. Note=In sperm, secretion gradually increases during capacitation.
蛋白家族：

NnrE/AIBP family
組織特異性：

Detected in testis and sperm (at protein level). Expressed at high levels in heart, liver, kidney, and testis.
數(shù)據(jù)庫鏈接：

KEGG: mmu:246703

STRING: 10090.ENSMUSP00000029708

UniGene: Mm.205996